Burak Kürsad Günhan
Senior Principal Biostatistician
Merck Healthcare KGaA (Darmstadt, Germany)
I am a Senior Principal Biostatistician at Merck Healthcare KGaA (Darmstadt, Germany), where I work on early phase oncology trials. My work focuses on Bayesian methods, dose-escalation trials, and evidence synthesis, with a particular interest in developing practical statistical methods for clinical drug development. Previously, I received my PhD in biostatistics from the University Medical Center Göttingen.
See my resumé.
Interests
- Phase I dose-escalation trials
- Bayesian statistics
- Hierarchical models
- Network meta-analysis
Education
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PhD in Biostatistics, 2020
University Medical Center Göttingen
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MSc in Biostatistics, 2016
University of Zurich
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BSc in Mathematics, 2012
Bogazici University (Istanbul)
Experience
Senior Biostatistician
Merck Healthcare KGaA
Biostatistician (Intern)
Galapagos NV
Developing a shrinkage estimation method for phase II trials with multiple treatment schedules
Biostatistician (Intern)
Novartis Pharma AG
Developed a Bayesian method for simultaneously optimizing dose and schedule in phase I oncology dose-escalation trials
Research Associate
University Medical Center Göttingen
Responsibilities include:
- Methodological research in early clinical trials and meta-analysis
- Statistical programming
- Teaching
Biostatistician (Intern)
F. Hoffmann-La Roche AG
Implemented nonlinear mixed effect models and pharmacokinetic pharmacodynamic models in Stan
Publications
A Bayesian time-to-event pharmacokinetic model for phase I dose-escalation trials with multiple schedules
We developed a method to analysze phase I dose-escalation trials with mutiple schedules.
